Genetic Factors in Generalized Osteo-Arthrosis
نویسندگان
چکیده
منابع مشابه
Genetic Factors in Generalized Osteo-arthrosis.
The occurrence of osteo-arthrosis in multiple joints was noted by Adams (1857). Cecil and Archer (1926) observed that the condition was more often polyarticular than monarticular in patients attending their rheumatism clinic, occurred mainly in middle-aged females, and was usually associated with Heberden's nodes; they labelled the condition menopausal arthritis. Stecher (1941, 1955) investigat...
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In a previous study (Kellgren and Bier, 1956), three sets of x rays of the hands were used to assess interand intra-observer differences in interpreting changes of rheumatoid arthritis. Wide disagreement between observers was found, and it was concluded that, to ensure maximum uniformity in grading x rays in field surveys and therapeutic trials, all readings should be made by the same observer,...
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There is no doubt about the value of intraarticular hydrocortisone in the treatment of rheumatoid arthritis. Controversy has arisen however about its value in the treatment of osteo-arthrosis. Hollander, who introduced this useful form of therapy, has remained an advocate of its use in both conditions (Hollander, 1966). Because of the lack of distinction between the response in patients with rh...
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This study of osteo-arthrosis, or degenerative joint disease, is based on the same survey material as the corresponding paper on rheumatoid arthritis (Kellgren and Lawrence, 1956). A one-in-ten random sample of the population aged 55-64 years in the Lancashire town of Leigh was studied clinically, radiologically, and serologically for all forms of arthritis. After a detailed clinical examinatio...
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Muscle and bone share numerous signaling pathways in the regulation of bone and muscle mass. However, of some crucial bone mass regulatory factors, such as RANKL, it is not known whether they are expressed in muscle, or whether they have an effect on muscle physiology. In addition, for some factors that are expressed in muscle and bone alike, i.e. COX-2, BMPs, Wnt signaling proteins, it is know...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1963
ISSN: 0003-4967
DOI: 10.1136/ard.22.4.237